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After seeing his take on 'You Da One,' Rihanna reveals she's in talks to appear alongside the actor in 'The Apocalypse.'
By Jocelyn Vena, with reporting by Josh Horowitz
Rihanna at "MTV First: Battleship"
Photo: MTV News
Rihanna and James Franco might want to get a room. These two have been gushing about one another all over the press — but, it's just business.
MTV News caught up with Franco at CinemaCon in Las Vegas, where he opened up about almost being cast in Ri's "We Found Love" video and how the pair might eventually appear together in the flick "The Apocalypse." RiRi later revealed that she's just as big a fan of Franco's work as he is of hers. How big of a fan is he? Well, the actor recently released a viral video of himself lip-syncing "You Da One."
"I love James Franco," Rihanna told MTV News during "MTV First: Battleship." Referring to the online video of Franco singing his heart out to her Dr. Luke-produced Talk That Talk single, she added, "Someone sent this to me via Twitter, and I watched that. I cried laughing."
After learning that the frizzy-haired man in the clip was indeed the Oscar-nominated actor, Rihanna couldn't believe he knew her music that well. "First of all, I didn't recognize that it was him like that, and then I didn't recognize it was him singing my song," she said. "And it was kind of cool because I'm a huge fan of James Franco, so it was dope to know that he even knew my record."
About the chatter that she might appear with Franco in Seth Rogen's movie "The Apocalypse," well, that is still up in the air. But if she should join him, she might be playing one of the celebs partying at Franco's house when they learn the apocalypse is coming. "That's in the works," she said. "I can't really say. Nothing's confirmed, but it's open, and we're interested."
Check out everything we've got on "Battleship."
For breaking news, celebrity columns, humor and more — updated around the clock — visit MTVMoviesBlog.com.
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Contact: Rebecca Hughes
hughes.r@ghc.org
206-287-2055
Group Health Research Institute
Choosing when to start regular breast cancer screening is a complicated decision for individual women and their providers. For most women, increasing age is the biggest risk factor for breast cancer, which is much more common at age 60 than at 40. But two new articles on other risk factors may inform guidelines and clinical practice about screening mammography from age 40 to 49.
The articles in the May 1 Annals of Internal Medicine provide information on how certain risk factors affect breast cancer risk and shift the balance between harms and benefits. Screening harms include false-positive results that can lead to invasive follow-up procedures and overdiagnosis, which prompts unnecessary treatment. Screening has a less favorable balance between benefits and harms in average-risk women in their 40s than in women aged 50 to 74.
This research addresses the need for more information about screening women in their 40sa need that the U.S. Preventive Services Task Force highlighted in its 2009 updated breast cancer screening guidelines. Also published in the Annals of Internal Medicine, these guidelines advise screening mammography every two years for women aged 50 to 74. The guidelines recommend that women in their 40s consider their personal values regarding the benefits and harms and then decide when to begin regular screening.
Group Health Research Institute Senior Investigators Diana Miglioretti, PhD, and Diana Buist, PhD, contributed to both of the new Annals articles. Together, the companion articles estimate that the benefits and harms of getting screening mammograms every two years are the same for groups of women aged 40-49 who have a twofold increased risk level of breast cancer as for groups of women aged 50? with an average breast cancer risk level. Factors that increase 40- to 49-year-old women's risk by twofold are having a first-degree relative (parent, sibling, or child) with breast cancer, or having extremely dense breast tissue (as seen on a mammogram).
"Mainly, we wanted to find out the tipping point: what level of increased risk women in their 40s needed to have to reach the same benefit-to-harm ratio for screening mammography as women aged 50 to 74," said Dr. Miglioretti. The international research team used data from the Breast Cancer Surveillance Consortium (BCSC), a U.S. research network of mammography registries. The BCSC is the nation's largest longitudinal collection of breast imaging data, covering 9.5 million mammograms, 2.3 million women, and 114,000 breast cancer cases so far. By continuously collecting information on breast cancer screening, risk factors, and cancer outcomes, the BCSC provides long-term data on screening as it occurs in everyday clinical practice to help answer preventive health care questions.
Tipping the balance of benefits and harms to favor screening mammography starting at age 40 years
In one article, Nicolien van Ravesteyn, MSc, Jeanne Mandelblatt, MD, MPH, and colleagues including Drs. Miglioretti and Buist identified the threshold of risk needed for women ages 40? to have comparable benefits and harms as seen when average-risk women aged 50? are screened every other year using mammography. They used four independent well-established simulation models that are part of the National Cancer Institute's Cancer Intervention and Surveillance Modeling Network (CISNET) collaborative. Ms. van Ravesteyn is a researcher at Erasmus Medical Center in Rotterdam, The Netherlands; and Dr. Mandelblatt is the associate director for population sciences at Georgetown University Medical Center's Lombardi Comprehensive Cancer Center in Washington, DC.
To estimate the benefits and harms of mammography screening for women in their 40s, the CISNET models used BCSC and other information on large populations of U.S. women. The results indicated that the benefits and harms from screening mammograms every two years for women 40-49 with a twofold increase in breast cancer risk are similar to those for average-risk women who start biennial screening at age 50. For annual screening, a fourfold increased risk level is where the benefits outweigh the harms for starting screening at age 40. There were only small differences in benefits using digital compared to plain-film mammography, but digital screening generates many more false-positive results than does plain film.
"Our population models show what can be expected across populations with different risk levels," Dr. Mandelblatt said. "The models cannot determine outcomes for individual women. Policymakers can use them to inform guidelines for populations."
Risk factors for breast cancer for women aged 40 to 49 years
The first author of the other article is Heidi D. Nelson, MD, MPH, an investigator at the Oregon Evidence-based Practice Center at Oregon Health & Science University and Providence Cancer Center in Portland. With Drs. Buist and Miglioretti and colleagues including Ellen O'Meara, PhD, a research associate at Group Health Research Institute, Dr. Nelson conducted a meta-analysisa rigorous review of previous studiesfrom 66 publications selected for their relevance and quality. They also conducted new analyses using BCSC data on more than 380,000 women who were 40-49 when they had a screening mammogram from 1994 to 2010, to see how family history and other risk factors affected breast cancer risk for women in their 40s.
Results indicated:
"Most of the risk factors that we considered did not increase breast cancer risk," Dr. Nelson said. Other potential risk factors that they evaluatedsuch as race/ethnicity, body mass index, physical activity, and using alcohol, tobacco, or hormone therapyhad effects that were either small, undetectable, or equivocal. "Our results indicate that we can focus on just a few significant risk factors to simplify approaches to risk-based screening for women in their 40s," she added.
The research in the two articles was possible because three national research groupsBCSC, CISNET, and the Evidence-based Practice Centerjoined forces. Each contributed unique strengths: extensive data, comprehensive breast cancer models, and data interpretation. The U.S. Preventive Services Task Force previously used information from the three groups to develop its current breast cancer screening recommendations.
In an accompanying editorial, Otis Webb Brawley, MD, chief medical officer and executive vice president of the American Cancer Society and author of the book How We Harm, referred to the BCSC and CISNET as "national treasures."
The authors called for additional research based on the findings, to see how well these risk estimates, which are based on large numbers of women, predict risks for individual women. In the meantime, said Dr. Buist, "taken together, the results from these articles provide strong evidence that professional groups can use to refine screening guidelines."
###
Funding was from the National Cancer Institute. The collaboration between BCSC, CISNET, and the Evidence-based Practice Center was supported in part by the 2009 American Recovery and Reinvestment Act (ARRA) and by the National Cancer Institute, which recently awarded a $20 million National Cancer Institute Program Project grant, co-led by Dr. Miglioretti, to the BCSC.
Ms. van Ravesteyn and Drs. Mandelblatt, Nelson, Buist, Miglioretti, and O'Meara's collaborators were Bernadette Zakher, MBBS, Amy Cantor, MD, MPH, Rongwei Fu, PhD, and Jessica Griffin, MS, of the Oregon Evidence-based Practice Center, Oregon Health & Science University, in Portland; Eveline A.M. Heijnsdijk, PhD, and Harry J. de Koning, MD, PhD, of Erasmus MC, in Rotterdam, The Netherlands; Karla Kerlikowske, MD, MS, of the University of California San Francisco; Amy Trentham-Dietz, PhD, and Oguzhan Alagoz, PhD, of the University of Wisconsin, Madison; Natasha K. Stout, PhD, of Harvard Medical School in Boston; Sandra J. Lee, DSc, and Hui Huang, MS, of Dana-Farber Cancer Institute in Boston; Clyde B. Schechter, MD, MA, of Albert Einstein College of Medicine in New York; and Aimee M. Near, MPH, of Georgetown University Medical Center and Lombardi Comprehensive Cancer Center in Washington DC.
Breast Cancer Surveillance Consortium
The Breast Cancer Surveillance Consortium (BCSC) is the nation's largest and most comprehensive collection of breast cancer screening information. It's a research resource for studies designed to assess the delivery and quality of breast cancer screening and related patient outcomes in the United States. The BCSC is a National Cancer Institute-funded collaborative network of seven mammography registries with linkages to tumor and/or pathology registries. The network is supported by a central Statistical Coordinating Center. Currently, the Consortium's database contains information on over 9.5 million mammographic examinations, 2.3 million women, and 114,000 breast cancer cases (95,000 invasive cancers and 19,000 ductal carcinoma in situ). More information: http://breastscreening.cancer.gov.
Cancer Intervention and Surveillance Modeling Network
The Cancer Intervention and Surveillance Modeling Network (CISNET) is a consortium of NCI-sponsored investigators that use statistical modeling to improve our understanding of cancer control interventions in prevention, screening, and treatment and their effects on population trends in incidence and mortality. These models can be used to guide public health research and priorities. More information: http://cisnet.cancer.gov.
Oregon Evidence-based Practice Center
The Oregon Evidence-based Practice Center (Oregon EPC) conducts systematic reviews of health care topics for federal and state agencies and private foundations. These reviews report the evidence from clinical research studies and the quality of that evidence for use by policymakers in decisions on guidelines and coverage. The Center is one of 14 EPCs sponsored by the Agency for Healthcare Research and Quality (AHRQ). More information: http://www.ohsu.edu/xd/research/centers-institutes/evidence-based-practice-ce....
Group Health Research Institute
Founded in 1947, Group Health Cooperative is a Seattle-based, consumer-governed, nonprofit health care system. Group Health Research Institute changed its name from Group Health Center for Health Studies in 2009. Since 1983, the Institute has conducted nonproprietary public-interest research on preventing, diagnosing, and treating major health problems. Government and private research grants provide its main funding. More information: http://grouphealthresearch.org.
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Contact: Rebecca Hughes
hughes.r@ghc.org
206-287-2055
Group Health Research Institute
Choosing when to start regular breast cancer screening is a complicated decision for individual women and their providers. For most women, increasing age is the biggest risk factor for breast cancer, which is much more common at age 60 than at 40. But two new articles on other risk factors may inform guidelines and clinical practice about screening mammography from age 40 to 49.
The articles in the May 1 Annals of Internal Medicine provide information on how certain risk factors affect breast cancer risk and shift the balance between harms and benefits. Screening harms include false-positive results that can lead to invasive follow-up procedures and overdiagnosis, which prompts unnecessary treatment. Screening has a less favorable balance between benefits and harms in average-risk women in their 40s than in women aged 50 to 74.
This research addresses the need for more information about screening women in their 40sa need that the U.S. Preventive Services Task Force highlighted in its 2009 updated breast cancer screening guidelines. Also published in the Annals of Internal Medicine, these guidelines advise screening mammography every two years for women aged 50 to 74. The guidelines recommend that women in their 40s consider their personal values regarding the benefits and harms and then decide when to begin regular screening.
Group Health Research Institute Senior Investigators Diana Miglioretti, PhD, and Diana Buist, PhD, contributed to both of the new Annals articles. Together, the companion articles estimate that the benefits and harms of getting screening mammograms every two years are the same for groups of women aged 40-49 who have a twofold increased risk level of breast cancer as for groups of women aged 50? with an average breast cancer risk level. Factors that increase 40- to 49-year-old women's risk by twofold are having a first-degree relative (parent, sibling, or child) with breast cancer, or having extremely dense breast tissue (as seen on a mammogram).
"Mainly, we wanted to find out the tipping point: what level of increased risk women in their 40s needed to have to reach the same benefit-to-harm ratio for screening mammography as women aged 50 to 74," said Dr. Miglioretti. The international research team used data from the Breast Cancer Surveillance Consortium (BCSC), a U.S. research network of mammography registries. The BCSC is the nation's largest longitudinal collection of breast imaging data, covering 9.5 million mammograms, 2.3 million women, and 114,000 breast cancer cases so far. By continuously collecting information on breast cancer screening, risk factors, and cancer outcomes, the BCSC provides long-term data on screening as it occurs in everyday clinical practice to help answer preventive health care questions.
Tipping the balance of benefits and harms to favor screening mammography starting at age 40 years
In one article, Nicolien van Ravesteyn, MSc, Jeanne Mandelblatt, MD, MPH, and colleagues including Drs. Miglioretti and Buist identified the threshold of risk needed for women ages 40? to have comparable benefits and harms as seen when average-risk women aged 50? are screened every other year using mammography. They used four independent well-established simulation models that are part of the National Cancer Institute's Cancer Intervention and Surveillance Modeling Network (CISNET) collaborative. Ms. van Ravesteyn is a researcher at Erasmus Medical Center in Rotterdam, The Netherlands; and Dr. Mandelblatt is the associate director for population sciences at Georgetown University Medical Center's Lombardi Comprehensive Cancer Center in Washington, DC.
To estimate the benefits and harms of mammography screening for women in their 40s, the CISNET models used BCSC and other information on large populations of U.S. women. The results indicated that the benefits and harms from screening mammograms every two years for women 40-49 with a twofold increase in breast cancer risk are similar to those for average-risk women who start biennial screening at age 50. For annual screening, a fourfold increased risk level is where the benefits outweigh the harms for starting screening at age 40. There were only small differences in benefits using digital compared to plain-film mammography, but digital screening generates many more false-positive results than does plain film.
"Our population models show what can be expected across populations with different risk levels," Dr. Mandelblatt said. "The models cannot determine outcomes for individual women. Policymakers can use them to inform guidelines for populations."
Risk factors for breast cancer for women aged 40 to 49 years
The first author of the other article is Heidi D. Nelson, MD, MPH, an investigator at the Oregon Evidence-based Practice Center at Oregon Health & Science University and Providence Cancer Center in Portland. With Drs. Buist and Miglioretti and colleagues including Ellen O'Meara, PhD, a research associate at Group Health Research Institute, Dr. Nelson conducted a meta-analysisa rigorous review of previous studiesfrom 66 publications selected for their relevance and quality. They also conducted new analyses using BCSC data on more than 380,000 women who were 40-49 when they had a screening mammogram from 1994 to 2010, to see how family history and other risk factors affected breast cancer risk for women in their 40s.
Results indicated:
"Most of the risk factors that we considered did not increase breast cancer risk," Dr. Nelson said. Other potential risk factors that they evaluatedsuch as race/ethnicity, body mass index, physical activity, and using alcohol, tobacco, or hormone therapyhad effects that were either small, undetectable, or equivocal. "Our results indicate that we can focus on just a few significant risk factors to simplify approaches to risk-based screening for women in their 40s," she added.
The research in the two articles was possible because three national research groupsBCSC, CISNET, and the Evidence-based Practice Centerjoined forces. Each contributed unique strengths: extensive data, comprehensive breast cancer models, and data interpretation. The U.S. Preventive Services Task Force previously used information from the three groups to develop its current breast cancer screening recommendations.
In an accompanying editorial, Otis Webb Brawley, MD, chief medical officer and executive vice president of the American Cancer Society and author of the book How We Harm, referred to the BCSC and CISNET as "national treasures."
The authors called for additional research based on the findings, to see how well these risk estimates, which are based on large numbers of women, predict risks for individual women. In the meantime, said Dr. Buist, "taken together, the results from these articles provide strong evidence that professional groups can use to refine screening guidelines."
###
Funding was from the National Cancer Institute. The collaboration between BCSC, CISNET, and the Evidence-based Practice Center was supported in part by the 2009 American Recovery and Reinvestment Act (ARRA) and by the National Cancer Institute, which recently awarded a $20 million National Cancer Institute Program Project grant, co-led by Dr. Miglioretti, to the BCSC.
Ms. van Ravesteyn and Drs. Mandelblatt, Nelson, Buist, Miglioretti, and O'Meara's collaborators were Bernadette Zakher, MBBS, Amy Cantor, MD, MPH, Rongwei Fu, PhD, and Jessica Griffin, MS, of the Oregon Evidence-based Practice Center, Oregon Health & Science University, in Portland; Eveline A.M. Heijnsdijk, PhD, and Harry J. de Koning, MD, PhD, of Erasmus MC, in Rotterdam, The Netherlands; Karla Kerlikowske, MD, MS, of the University of California San Francisco; Amy Trentham-Dietz, PhD, and Oguzhan Alagoz, PhD, of the University of Wisconsin, Madison; Natasha K. Stout, PhD, of Harvard Medical School in Boston; Sandra J. Lee, DSc, and Hui Huang, MS, of Dana-Farber Cancer Institute in Boston; Clyde B. Schechter, MD, MA, of Albert Einstein College of Medicine in New York; and Aimee M. Near, MPH, of Georgetown University Medical Center and Lombardi Comprehensive Cancer Center in Washington DC.
Breast Cancer Surveillance Consortium
The Breast Cancer Surveillance Consortium (BCSC) is the nation's largest and most comprehensive collection of breast cancer screening information. It's a research resource for studies designed to assess the delivery and quality of breast cancer screening and related patient outcomes in the United States. The BCSC is a National Cancer Institute-funded collaborative network of seven mammography registries with linkages to tumor and/or pathology registries. The network is supported by a central Statistical Coordinating Center. Currently, the Consortium's database contains information on over 9.5 million mammographic examinations, 2.3 million women, and 114,000 breast cancer cases (95,000 invasive cancers and 19,000 ductal carcinoma in situ). More information: http://breastscreening.cancer.gov.
Cancer Intervention and Surveillance Modeling Network
The Cancer Intervention and Surveillance Modeling Network (CISNET) is a consortium of NCI-sponsored investigators that use statistical modeling to improve our understanding of cancer control interventions in prevention, screening, and treatment and their effects on population trends in incidence and mortality. These models can be used to guide public health research and priorities. More information: http://cisnet.cancer.gov.
Oregon Evidence-based Practice Center
The Oregon Evidence-based Practice Center (Oregon EPC) conducts systematic reviews of health care topics for federal and state agencies and private foundations. These reviews report the evidence from clinical research studies and the quality of that evidence for use by policymakers in decisions on guidelines and coverage. The Center is one of 14 EPCs sponsored by the Agency for Healthcare Research and Quality (AHRQ). More information: http://www.ohsu.edu/xd/research/centers-institutes/evidence-based-practice-ce....
Group Health Research Institute
Founded in 1947, Group Health Cooperative is a Seattle-based, consumer-governed, nonprofit health care system. Group Health Research Institute changed its name from Group Health Center for Health Studies in 2009. Since 1983, the Institute has conducted nonproprietary public-interest research on preventing, diagnosing, and treating major health problems. Government and private research grants provide its main funding. More information: http://grouphealthresearch.org.
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
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Socialcam is hustling to be the "Instagram for video" app of choice, battling neck-and-neck for the top spot in the iTunes app store with its main rival, Viddy. It turns out that Socialcam now has a number of very powerful people rooting for it to win: An angel investor list that reads like a "who's who" of tech and entertainment industry heavyweights. I've been hearing whispers about Socialcam's crazy angel round for weeks now, and I've finally verified the full list of the startup's seed backers. I've pasted the entire list at the bottom of this post, but the names include Tim Draper, Yuri Milner, Ari Emmanuel, Laurene Powell Jobs, Ashton Kutcher, Brian Chesky, Paul Buchheit, Alexis Ohanian, and many more.pauly d project faith hill autism obamacare adrienne rich cesar chavez day raspberry ketone
Welcome to THG's Week in Review! Below, our staffers look back at the stories, stars and scandals that made the last seven days some of the craziest ALL MONTH.
If you don't already, FOLLOW THG on Twitter, Google+ and Facebook for 24/7/365 news. Every day, week and year, let us be your celebrity gossip source!
Now, a rundown of the week that was at The Hollywood Gossip:
What was the highlight of the week for you? Did we leave anything out?
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